Orthopaedic Innovation

Research paper

Femoral and Tibial Tunnel Positioning on Graft Isometry in Anterior Cruciate Ligament Reconstruction: A Cadaveric Study

This cadaveric study investigated the critical relationship between femoral and tibial tunnel positions and graft isometry during anterior cruciate ligament (ACL) reconstruction. By analysing distance changes between different tunnel combinations in 11 cadaveric knees, the research provides valuable insights into how surgical choices can impact the stability of the new graft and, consequently, long-term patient outcomes.

Key Findings on Graft Isometry

The study’s primary finding confirmed that no single graft position is perfectly isometric, meaning the graft’s length changes slightly throughout the knee’s full range of motion. To reach this conclusion, the authors meticulously tested three different femoral tunnel placements and three tibial tunnel placements. They paired these in various combinations and measured the distance change, or anisometry, as the knee moved through a range of motion from 0°, 90°, to 135°.

The researchers discovered that the most isometric configuration, demonstrating the least amount of change in length, was a specific combination of tunnel placements. This occurred with a femoral tunnel positioned at the anteromedial bundle site and a more anterior tibial insertion, resulting in a mean change of approximately 2.78 ± 0.93 mm. This is significant because a graft with minimal length change is less likely to be subjected to excessive tension or laxity, thereby reducing the risk of stretching or rupture.

Conversely, the study found the least isometric configuration exhibited the largest change, a mean of approximately 10.37 ± 2.08 mm. This was the result of placing the femoral tunnel in the mid-bundle position and the tibial tunnel in the posterolateral bundle insertion.

The research also highlighted that the femoral tunnel position had a greater influence on graft isometry than the tibial tunnel position. This finding underscores the importance of precise femoral tunnel placement as a key factor for surgeons to consider during the reconstruction procedure.

Implications for Surgical Technique

This study provides an evidence-based rationale for surgical planning in ACL reconstruction. While traditional techniques may not always achieve optimal graft isometry, this research supports a modern approach that prioritizes precise, anatomical tunnel placement. By aiming for the anteromedial femoral and anterior tibial tunnel combination, surgeons can enhance graft stability, potentially leading to a more durable and effective reconstruction.

The use of cadaveric knees allowed for meticulous, repeated measurements under controlled conditions, providing robust data to guide clinical practice. These findings contribute to the ongoing evolution of ACL reconstruction techniques, helping to improve functional outcomes for patients. 

Professor Wilson’s Comments

“This was a tough but very rewarding study. We travelled to Munich to the Arthrex cadaveric facility, where we were each given eleven cadaveric knees to work on. I took six and my registrar at the time took five. On each knee, we drilled tunnels in three positions on the femur and three on the tibia, then ran a suture or tape in every possible combination — front to front, front to middle, front to back, and so on. By the end of the day, we were completely exhausted, having effectively performed dozens of ACL reconstructions.

However, the effort was well worth it. The study provided valuable insights into length change and asymmetry during ACL reconstruction, helping us better understand the impact of tunnel positioning. This was not only significant for my own surgical development but also for other surgeons who have since learnt from this paper. It reinforced a key principle in ACL surgery: precision matters. Being even one or two millimetres out in tunnel placement can make the difference between an excellent and a suboptimal outcome — it’s all about attention to detail.”

To delve into the complete findings, methodology, and analysis, the full research paper is available for your perusal.

Femoral and Tibial Tunnel Positioning on Graft Isometry in Anterior Cruciate Ligament Reconstruction: A Cadaveric Study

Sources used in report overview:

  1. https://pubmed.ncbi.nlm.nih.gov/25550010/
  2. https://www.researchgate.net/publication/270290421_Femoral_and_Tibial_Tunnel_Positioning_on_Graft_Isometry_in_Anterior_Cruciate_Ligament_Reconstruction_A_Cadaveric_Study
  3. https://www.wheelessonline.com/muscles-tendons/acl-graft-placement-theory/

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