Cushioning your joint, delaying surgery, improving quality of life
Knee osteoarthritis often leaves patients caught between conservative therapies that no longer suffice and the prospect of surgery. At Orthopaedic Innovation, we offer a range of treatments, and one of the advanced non-surgical options is Arthrosamid® injection. This injectable hydrogel implant is designed to cushion the joint, reduce pain, and preserve mobility over the longer term.
In this blog, we’ll cover how Arthrosamid works, when it’s appropriate, what patients can expect, benefits, limitations, and how it compares to other injectables.
What Is Arthrosamid®?
Arthrosamid® is a non-biodegradable polyacrylamide hydrogel (iPAAG, 2.5%) that is injected into the joint space to act as a permanent soft scaffold within the synovial lining. Unlike temporary viscosupplementation injections, Arthrosamid integrates with the joint to deliver long-lasting symptom relief.
Because it remains in place, Arthrosamid provides mechanical cushioning and helps restore lubrication — reducing pain and improving function for patients with mild to moderate knee osteoarthritis.
Read all about non-surgical treatments in our blog: Non-Surgical Treatments for Knee Pain: What Are Your Options?
How Does Arthrosamid Work?
- Injection & Integration: Administered under local anaesthesia, the hydrogel integrates with the synovial membrane, creating a soft scaffold that thickens the joint lining.
- Cushioning & Lubrication: This helps reduce friction, alleviates pain, and improves mobility.
- Long-Term Support: Since the hydrogel is non-degradable, it provides ongoing mechanical support, with published studies showing improvements lasting at least 12 months after a single injection - Study in National Library of Medicine1
Benefits of Arthrosamid Injections
- Provides sustained pain relief and functional improvement
- Minimally invasive and performed as an outpatient procedure
- May delay or reduce the need for knee replacement surgery
- Bone and cartilage-preserving approach
- Permanent implant with no need for repeat injections in the short term
Dive deeper on the official Arthrosamid website2
Is Arthrosamid Right for You?
Arthrosamid injections are best suited for patients with mild to moderate knee osteoarthritis who:
- Continue to have pain despite conservative treatments
- Are not ready for, or wish to delay, knee replacement surgery
- Have relatively stable knee alignment and ligaments
Patients with severe bone-on-bone arthritis or significant deformity may still benefit more from surgical options such as knee replacement surgery.
Frequently Asked Questions
- How soon will I notice results?
Many patients experience pain relief within weeks of treatment, though full effect can take longer as the hydrogel integrates. - How long does it last?
Clinical studies report sustained improvements in pain, stiffness, and mobility for at least 12 months, with potential benefits extending beyond that. - Can Arthrosamid Injections replace knee replacement surgery? It may delay or reduce the need for surgery but is not a substitute in cases of advanced arthritis.
Take the First Step Toward Joint Relief
At Orthopaedic Innovation, we’re committed to providing innovative, evidence-based solutions for knee osteoarthritis. Arthrosamid offers patients a safe, minimally invasive treatment that may improve quality of life and delay the need for surgery. Read more about our Arthrosamid injection treatment option.
If you’re struggling with knee pain, Contact Us today to discuss whether Arthrosamid is right for you.
1https://pmc.ncbi.nlm.nih.gov/articles/PMC11064315
2https://arthrosamid.com/our-solution
